A case of cutaneous extranodal natural killer/T‐cell lymphoma clinically and histopathologically mimicking interface dermatitis. (2nd June 2020)

• Record Type: Journal Article
• Authors: Choi, Myoung Eun; Yang, Hee Joo; Lee, Woo Jin; Won, Chong Hyun; Chang, Sung Eun; Choi, Jee Ho; Lee, Mi Woo
• Is Part Of: Australasian journal of dermatology. Volume 61:Number 4(2020)
• Page Start: e410
• Page End: e413
• Publication Date: 2020-06-02
• Subjects: lichenoid eruptions -- lymphoma -- natural killer cells -- prognosis -- skin; Dermatology -- Periodicals; Dermatology -- Australasia -- Periodicals; 616.5005
• DOI: 10.1111/ajd.13304
• Languages: English
• ISSNs: 0004-8380

Abstract

Abstract: Extranodal natural killer/T‐cell lymphoma (ENKTL) is a rare but aggressive cancer characterised by angiocentric and angiodestructive infiltration by NK‐cells, or cytotoxic T‐cell types. Histopathologically, ENKTL shows a multinodular or diffuse infiltration localised to vascular structures, resulting in angiodestruction and necrosis. We present a patient with an initially suspected diagnosis of benign interface dermatitis with a differential diagnosis of mycosis fungoides that was later found to be an aggressive extranodal natural killer/T‐cell lymphoma of a nasal type and with a dismal prognosis.