Development of evidence‐based consensus on critical issues in the management of patients with vitiligo: A modified Delphi study. Issue 1 (10th September 2020)

• Record Type: Journal Article
• Authors: Bae, Jung Min; Jeong, Ki‐Heon; Choi, Chong Won; Park, Ji Hun; Lee, Hee Jung; Kim, Hee Jung; Lee, Sang Hoon; Oh, Sang Ho; Shin, Jeonghyun; Kang, Hee Young; Lee, Weon Ju; Ju, Hyun Jeong; Kim, Dong Hyun; Chang, Sung Eun; Lee, Dong Youn; Kim, You Chan; Choi, Gwang Seong; Kim, Ki‐Ho; Kim, Tae Heung; Lee, Seung Chul; Lee, Ai‐Young; Hann, Seung‐Kyung; Lee, Mu‐Hyoung; Park, Chul Jong
• Is Part Of: Photodermatology, photoimmunology & photomedicine. Volume 37:Issue 1(2021)
• Page Start: 3
• Page End: 11
• Publication Date: 2020-09-10
• Subjects: Delphi -- expert -- guideline -- recommendation -- surgery -- treatment -- vitiligo; Photosensitivity disorders -- Periodicals; Dermatology -- Periodicals; Immunology -- Periodicals; 616.5
• DOI: 10.1111/phpp.12598
• Languages: English
• ISSNs: 0905-4383

Abstract

Abstract: Background/purpose: Vitiligo remains a major challenge in dermatology. However, much of the treatment remains unclear, because little evidence is available. We sought to answer some critical questions pertaining to management of vitiligo patients. Methods: A modified Delphi process among 31 vitiligo experts was conducted. A total of 12 clinical vitiligo treatment questions without clear answers were collected via a vote. To address each question, two members performed systematic literature reviews and prepared draft statements along with the levels of evidence and strength of recommendation. After reviewing the draft, all expressed their extent of agreement from 1 (strong disagreement) to 9 (strong agreement) for each item. The drafts were revised to reflect suggested comments. Discussion continued until all members agreed with the ultimate decision. Results: The consensus process was completed after five rounds. We identified the best answers to 12 key questions, including issues on long‐term phototherapy, systemic and topical corticosteroids, topical calcineurin inhibitors, immunosuppressants, excimer laser treatment, and surgical interventions. Conclusion: This consensus would complement current guidelines and aid both physician and patient decision‐making in the treatment of vitiligo.