Cover Feature: Short RNA Universal Coding for Topological Transformation Nano‐barcoding Application (ChemBioChem 2/2021). (4th January 2021)

• Record Type: Journal Article
• Authors: Kim, Jeonghun; Moon, Je Hun; Um, Soong Ho
• Is Part Of: Chembiochem. Volume 22:Number 2(2021)
• Page Start: 261
• Page End: 261
• Publication Date: 2021-01-04
• Subjects: EGFR -- micro RNA -- nano-barcoding -- shorter RNA fragments -- topological transformation -- universal coding; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.202000860
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : Disease diagnosis and prognosis through the detection of genetic biomarkers occupy an important part in molecular biology. Considering the thermodynamics of the strand‐displacement reaction, we studied a system that can convert various miRNAs into a code that makes the detection system work. The cover feature reflects this discovery and shows that miRNAs in various sequences are transformed into the universal code and act as the key to operating a topological transformation nanobarcoding system that specializes in target detection. More information can be found in the full paper by S. H. Um et al.