Cultivation of Rat Nerve Cells on Nanoimprinted Microstructures on Polydimethylsiloxane Sheets. (11th September 2015)

• Record Type: Journal Article
• Authors: Koshinuma, Eiki; Maenosono, Hirotaka; Endo, Daisuke; Nishioka, Yasushiro
• Is Part Of: ECS transactions. Volume 69:Number 13(2015)
• Page Start: 59
• Page End: 62
• Publication Date: 2015-09-11
• Subjects: Electrochemistry -- Periodicals; Electrochemistry; Periodicals; Electronic journals; Electronic journal; 541.37
• DOI: 10.1149/06913.0059ecst
• Languages: English
• ISSNs: 1938-5862

Abstract

Abstract : Regenerative medical research has attracted much attention in recent years. Here, we fabricated micro trench structures with varying widths of 15 and 150 μm and depths of 30 and 60 μm using the nanoimprint technique on a 100 μm thick polydimethylsiloxane culture sheet used as a biocompatible polymer culture sheet. Rat neurons were observed to grow after 3 days selectively within those micro trenches with widths larger than 15 μm, and they were coated with polylysine.