Guanosine-rich aptamers@Cu2O nanoparticles: enhanced peroxidase activity and specific recognition capability at neutral pH. Issue 5 (21st December 2020)

• Record Type: Journal Article
• Authors: Ma, Hongchao; Wang, Lan; Li, Yifan; Wei, Yanhui
• Is Part Of: Chemical communications. Volume 57:Issue 5(2021)
• Page Start: 643
• Page End: 646
• Publication Date: 2020-12-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc06877b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Decorating Cu2 O peroxidase mimic with guanosine-rich aptamers can "turn on" its peroxidase activity at neutral pH media and endow it with specific recognition capability, greatly expanding its application in biological fields. Abstract : The decoration of Cu2 O nanoparticles with guanosine-rich aptamers can significantly enhance their peroxidase activity at neutral pH and endow them with specific recognition capabilities. Both the phosphate backbone and guanine of the aptamers contribute to the enhancement. The excellent enzyme-like properties of this Cu2 O–aptamer system make it a versatile platform for the development of neutral pH biosensors.