Venetoclax Combined with Hypomethylating Agents for Treatment-Naïve B/Myeloid Mixed Phenotype Acute Leukemia. (12th January 2021)

• Record Type: Journal Article
• Authors: Wu, Di; Chen, Wenlan; Chen, Zhichao; Li, Qiubai
• Other Names: Shiozawa Yusuke Academic Editor.
• Is Part Of: Case reports in hematology. Volume 2021(2021)
• Publication Date: 2021-01-12
• Subjects: Hematology -- Periodicals; Hematology -- Case studies -- Periodicals; Blood -- Diseases -- Periodicals; Hematology; Hematologic Diseases; Blood -- Diseases; Hematology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.15
• DOI: 10.1155/2021/6661109
• Languages: English
• ISSNs: 2090-6560

Abstract

Abstract : Mixed phenotype acute leukemia (MPAL) is a rare hematological malignancy that lacks consensus on optimal management. We report for the first time two cases of treatment-naïve B/myeloid MPAL patients treated with a novel chemo-free regimen using venetoclax combined with hypomethylating agents, which successfully induced complete remission with tolerable toxicities.