Goblet cell adenocarcinoma: concepts and updates. Issue 2 (February 2021)

• Record Type: Journal Article
• Authors: Hosseini, Mojgan; Ronquillo, Nemencio
• Is Part Of: Diagnostic histopathology. Volume 27:Issue 2(2021)
• Page Start: 69
• Page End: 74
• Publication Date: 2021-02
• Subjects: adenocarcinoid -- adenocarcinoma -- adenocarcinoma ex goblet cell carcinoid -- adenoneuroendocrine -- appendix -- goblet cell carcinoid; Histology, Pathological -- Periodicals; Cytodiagnosis -- Periodicals; Diagnosis, Laboratory -- Periodicals; Pathology -- Periodicals; Histopathologie -- Périodiques; Pathologie -- Périodiques; Cytodiagnostics -- Périodiques; Diagnostics biologiques -- Périodiques; Histologie -- Technique -- Périodiques; Electronic journals; 616.07582
• DOI: 10.1016/j.mpdhp.2020.11.003
• Languages: English
• ISSNs: 1756-2317

Abstract

Abstract: Appendiceal goblet cell adenocarcinoma, previously called goblet cell carcinoid and adenocarcinoma ex goblet cell carcinoid, is a rare neoplasm that occurs almost exclusively in the appendix. Several classification and grading systems have been proposed that can separate patients into prognostic groups. This review will provide an update on various classification systems with emphasis on the newly published 2019 World Health Organization Classification of Tumors, which proposed a 3-tiered grading system for appendiceal goblet cell adenocarcinoma based on the extent of low and high-grade patterns.