Fluorescence assay of oxytetracycline in seawater after selective capture using magnetic molecularly imprinted nanoparticles. (February 2021)

• Record Type: Journal Article
• Authors: Zhao, Min; Wang, Jiangtao; Lian, Ziru
• Is Part Of: Marine pollution bulletin. Volume 163(2021)
• Publication Date: 2021-02
• Subjects: Oxytetracycline -- Seawater -- Fluorescence spectrophotometry -- Magnetic imprinted polymers -- Multivariate optimization; Marine pollution -- Periodicals; Marine Biology -- Periodicals; Water Pollution -- Periodicals; Mer -- Pollution -- Périodiques; Publications périodiques; Pollution des mers; Lutte antipollution; Electronic journals; 363.7394
• DOI: 10.1016/j.marpolbul.2020.111962
• Languages: English
• ISSNs: 0025-326X

Abstract

Abstract: A comprehensive strategy for manufacturing a novel sorbent based on magnetic molecularly imprinted polymers (MMIPs) is addressed for selective capture of oxytetracycline from seawater. The novel MMIPs were synthesized by nano-Fe3 O4 as sacrificial matrix and adsorption properties of the polymers demonstrate rapid adsorption kinetics, high adsorption capacity, and specificity towards oxytetracycline provided by the core-shell composite structure. After screening the critical parameters by multivariate optimization, a magnetic imprinting solid phase extraction method combined with fluorescence spectrophotometry (MMIP-SPE-FL) was constructed for sensitive determination of oxytetracycline in seawater samples. The results show a good linear response dependence on the spiking concentration of 3–100 μg L −1, and a satisfactory limit of detection of 0.7 μg L −1 after the MMIP-SPE preconcentration. Seven seawater samples from Jiaozhou bay were analyzed to give recoveries in the range of 89.75–107.65% with relative standard deviation values of less than 5.44% (n = 3). Graphical abstract: Unlabelled Image Highlights: Magnetic imprinted nanoparticles for oxytetracycline (OTC-MMIPs) were prepared. The MMIPs showed remarkable adsorption capacity, kinetics and selectivity. A MMIP-SPE procedure was developed for OTC selective extraction from seawater. Seawater samples from Jiaozhou bay were effectively analyzed by MMIP-SPE-FL.