Fluorescent cyclic peptides for cell imaging. Issue 1 (2nd July 2020)

• Record Type: Journal Article
• Authors: Mendive‐Tapia, Lorena; Wang, Jinling; Vendrell, Marc
• Other Names: Jamieson Andrew G. guestEditor.
• Is Part Of: Peptide science. Volume 113:Issue 1(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-07-02
• Subjects: amino acids -- cancer -- fluorescence -- inflammation -- probes; Peptides -- Periodicals; 572.6505
• DOI: 10.1002/pep2.24181
• Languages: English
• ISSNs: 2475-8817

Abstract

Abstract: Fluorescent cyclic peptides are excellent chemical scaffolds to build optical agents for molecular imaging. In addition to their favorable physicochemical properties, they can be modified with multiple organic fluorophores and generate useful probes for biological assays targeting specific proteins, namely receptors or enzymes. In this article, we review recent advances in the synthetic approaches for the preparation of fluorescent cyclic peptides as well as some of their applications in biological imaging, from in vitro live‐cell imaging studies to in vivo characterization of preclinical models. Abstract :