Developing a cosmetic series: Results from the ESSCA network, 2009‐2018. (29th September 2020)

• Record Type: Journal Article
• Authors: Horton, Emma; Uter, Wolfgang; Geier, Johannes; Ballmer‐Weber, Barbara; Bauer, Andrea; Bircher, Andreas; Dickel, Heinrich; Giménez‐Arnau, Ana; Gonçalo, Margarida; John, Swen Malte; Mahler, Vera; Schuttelaar, Marie L. A.; Simon, Dagmar; Sanchez‐Perez, Javier; Rustemeyer, Thomas; Weisshaar, Elke; Wilkinson, Mark
• Is Part Of: Contact dermatitis. Volume 84:Number 2(2021)
• Page Start: 82
• Page End: 94
• Publication Date: 2020-09-29
• Subjects: antioxidant -- antiseptic -- contact allergy -- cosmetic -- emollient -- emulsifier -- Europe -- patch testing -- preservative -- surfactant; Contact dermatitis -- Periodicals; 616.51
• DOI: 10.1111/cod.13690
• Languages: English
• ISSNs: 0105-1873

Abstract

Abstract: Background: There is considerable variability across European patch test centres as to which allergens are included in local and national cosmetics series. Objectives: To propose a standardized, evidence‐based cosmetic series for Europe based on up‐to‐date analysis of relevant contact allergens. Methods: We collated data from the European Surveillance System on Contact Allergies (ESSCA) from 2009 to 2018 to determine which cosmetic allergens produce a high yield of contact allergy. Contact allergens with a prevalence of >0.3% that were considered relevant were included. Rare contact allergens were excluded if deemed no longer relevant or added to a supplemental cosmetic series for further analysis. Results: Sensitization prevalences of 39 cosmetic contact allergens were tabulated. Thirty of these allergens yielded >0.3% positive reactions and are therefore included in our proposed European cosmetic series. Six were considered no longer relevant and therefore excluded. Three were included in a supplementary European cosmetic series. An additional nine allergens were included in either the core or supplemental European cosmetic series following literature review. Conclusion: We have derived a potential European cosmetic series based upon the above methods. This will require ongoing investigation based upon the changing exposure profiles of cosmetic allergens as well as new and evolving substances.