Primary vaginal leiomyosarcoma: case report of a rare gynaecological malignancy and diagnostic challenge in a resource-constraint setting. Issue 9 (22nd September 2020)

• Record Type: Journal Article
• Authors: Okunowo, Adeyemi A; Ugwu, Aloy O; Owie, Emmanuel; Kolawole, Habibat F; Adebayo, Luqman A; Kusamotu, Olaniyi A; Kuku, Jubril O; Soibi-Harry, Adaiah P; Ohazurike, Ephraim O; Banjo, Adekunbiola A F
• Is Part Of: Oxford medical case reports. Volume 2020:Issue 9(2020)
• Publication Date: 2020-09-22
• Subjects: Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1093/omcr/omaa081
• Languages: English
• ISSNs: 2053-8855

Abstract

ABSTRACT: Primary vaginal leiomyosarcoma (VLMS) is an extremely rare variant of primary vaginal cancers with very poor prognosis irrespective of the stage at presentation and the type of treatment received. It is easily recurrent and has a high propensity for haematogenous spread especially to the lungs. We present the case of a 34-year-old Para 1 + 1 (1 alive) woman with recurrent vaginal mass of 8 years duration after two surgical excisions without histological evaluation. She had examination under anaesthesia and a wide local excision of the vaginal mass. Histological examination of the mass revealed poorly differentiated VLMS with positive surgical margins and she was commenced on adjuvant chemo-radiation. Histological evaluation remains the hallmark for diagnosing rare malignancies like VLMS, which unfortunately is not a standard practice in some resource-constraint settings.