Mike Wakelam: an appreciation. Issue 3 (10th July 2020)
- Record Type:
- Journal Article
- Title:
- Mike Wakelam: an appreciation. Issue 3 (10th July 2020)
- Main Title:
- Mike Wakelam: an appreciation
- Authors:
- Michell, Bob
- Editors:
- Harwood, John
Lloyd-Evans, Emyr - Abstract:
- Abstract: This issue of Essays in Biochemistry explores lipid mediators — biologically active metabolites formed by enzymic and non-enzymic oxidation of polyunsaturated fatty acids. These can be exported across the cell membrane into the extracellular space, where they activate cell surface receptors to stimulate the cells of origin (autocrine) or nearby cells (paracrine). Lipid mediators are involved in many physiological processes, which may become dysregulated during ageing and in lipid-related diseases such as diabetes, atherosclerosis, arthritis, cancer, Alzheimer's disease and metabolic syndrome. Following the death in March 2020 of Professor Mike Wakelam, with the loss of his major input into the lipid signalling field, Portland Press and Guest Editors John Harwood and Emyr Lloyd-Evans decided to dedicate this issue to his memory. This Editorial briefly recalls his work and influence.
- Is Part Of:
- Essays in biochemistry. Volume 64:Issue 3(2020)
- Journal:
- Essays in biochemistry
- Issue:
- Volume 64:Issue 3(2020)
- Issue Display:
- Volume 64, Issue 3 (2020)
- Year:
- 2020
- Volume:
- 64
- Issue:
- 3
- Issue Sort Value:
- 2020-0064-0003-0000
- Page Start:
- 397
- Page End:
- 399
- Publication Date:
- 2020-07-10
- Subjects:
- autocrine pathways -- lipid mediators -- metabolism -- paracrine pathways
Biochemistry -- Periodicals
572 - Journal URLs:
- https://portlandpress.com/essaysbiochem ↗
- DOI:
- 10.1042/EBC20200042 ↗
- Languages:
- English
- ISSNs:
- 0071-1365
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 15432.xml