Periodontal disease in patients with chronic coronary heart disease: Prevalence and association with cardiovascular risk factors. (29th August 2020)

• Record Type: Journal Article
• Authors: Vedin, Ola; Hagström, Emil; Gallup, Dianne; Neely, Megan L; Stewart, Ralph; Koenig, Wolfgang; Budaj, Andrzej; Sritara, Piyamitr; Wallentin, Lars; White, Harvey D; Held, Claes
• Is Part Of: European journal of preventive cardiology. Volume 22:Number 6(2015)
• Page Start: 771
• Page End: 778
• Publication Date: 2020-08-29
• Subjects: Tooth loss -- gum bleeding -- periodontal disease -- coronary heart disease -- risk factors; Cardiovascular system -- Diseases -- Prevention -- Periodicals; Cardiac patients -- Rehabilitation -- Periodicals; 616.12
• DOI: 10.1177/2047487314530660
• Languages: English
• ISSNs: 2047-4873

Abstract

Abstract: Aim: There are reported links between periodontal disease (PD) and cardiovascular (CV) risk but data are lacking, especially from populations with established coronary heart disease (CHD). This study describes self-reported indicators of PD and associations with CV risk factors in a global stable CHD population. Methods and results: A total of 15, 828 participants in the global STABILITY trial underwent a physical examination, blood sampling, and completed a lifestyle questionnaire. They reported remaining number of teeth (none, 1 – 14, 15 – 20, 21 – 25 or 26 – 32 (all)) and frequency of gum bleeding (never/rarely, sometimes, often or always). Adjusted linear and logistic regression models assessed associations between tooth loss, gum bleeding, and socioeconomic and CV risk factors. A total of 40.9% of participants had <15 remaining teeth; 16.4% had no teeth; and 25.6% reported gum bleeding with large differences in prevalence among countries, regions and ethnic groups. Less tooth loss was associated with lower levels of glucose, low-density lipoprotein (LDL) cholesterol, systolic blood pressure, waist circumference and hs-CRP; higher estimated glomerular filtration rate; decreased odds for diabetes and smoking, and increased odds for higher education, alcohol consumption and work stress. Gum bleeding was associated with higher LDL cholesterol and systolic blood pressure; decreased odds for smoking, but increased odds for higher education, alcohol consumption and stress. Conclusion: Self-reported indicators of PD were common in this chronic CHD population and were associated with an increasing socioeconomic and CV risk factor burden. However, causality between self-reported PD and CV risk and outcome needs further investigation.