Carbohydrate-based vaccines: challenges and opportunities. (November 2010)

• Record Type: Journal Article
• Authors: Huang, Yen-Lin; Wu, Chung-Yi
• Is Part Of: Expert review of vaccines. Volume 9:Number 11(2010)
• Page Start: 1257
• Page End: 1274
• Publication Date: 2010-11
• Subjects: bacteria -- cancer -- carbohydrates -- parasites -- vaccine -- virus; Vaccines -- Periodicals; Vaccination -- Periodicals; 615.37205
• DOI: 10.1586/erv.10.120
• Languages: English
• ISSNs: 1476-0584

Abstract

Advances in the synthesis of oligo- or polysaccharides and new technologies developed in glycobiology studies have opened a new avenue in carbohydrate vaccine design. In principle, various types of cell-surface epitopes, characteristic of the invading organism or related to aberrant growth of cells, can be applied to develop vaccines. Numerous promising carbohydrate-based vaccine candidates have been prepared in recent years. This article, primarily for general readers, briefly presents the recent advances involving carbohydrate-based vaccines, including antibacterial, antiparasite, anticancer and antivirus vaccines.