Specific Considerations for Venovenous Extracorporeal Membrane Oxygenation During Coronavirus Disease 2019 Pandemic. Issue 10 (November 2020)

• Record Type: Journal Article
• Authors: Guihaire, Julien; Owyang, Clark g.; Madhok, Jai; Laverdure, Florent; Gaillard, Maïra; Girault, Antoine; Lebreton, Guillaume; Mercier, Olaf
• Is Part Of: ASAIO journal. Volume 66:Issue 10(2020)
• Publication Date: 2020-11
• Subjects: acute respiratory distress syndrome -- extracorporeal membrane oxygenation -- COVID-19 -- hemocompatibility -- anticoagulation; Artificial organs -- Periodicals; 617
• DOI: 10.1097/MAT.0000000000001251
• Languages: English
• ISSNs: 1058-2916

Abstract

Abstract : Extracorporeal membrane oxygenation (ECMO) is recognized as organ support for potentially reversible acute respiratory distress syndrome (ARDS). However, limited resource during the outbreak and the coagulopathy associated with coronavirus disease 2019 (COVID-19) make the utilization of venovenous (VV) ECMO highly challenging. We herein report specific considerations for cannulation configurations and ECMO management during the pandemic. High blood flow and anticoagulation at higher levels than usual practice for VV ECMO may be required because of thrombotic hematologic profile of COVID-19. Among our first 24 cases (48.8 ± 8.9 years), 17 patients were weaned from ECMO after a mean duration of 19.0 ± 10.1 days and 16 of them have been discharged from ICU.