Clinical characteristics and short term outcomes after recovery from COVID-19 in patients with and without diabetes in Bangladesh. Issue 6 (November 2020)

• Record Type: Journal Article
• Authors: Akter, Farhana; Mannan, Adnan; Mehedi, H.M. Hamidullah; Rob, Md. Abdur; Ahmed, Shakeel; Salauddin, Asma; Hossain, Md. Shakhawat; Hasan, Md. Mahbub
• Is Part Of: Diabetes & metabolic syndrome. Volume 14:Issue 6(2020)
• Page Start: 2031
• Page End: 2038
• Publication Date: 2020-11
• Subjects: Diabetes -- COVID-19 -- Bangladesh -- Comorbidities -- Insulin; Diabetes -- Periodicals; Metabolism -- Disorders -- Periodicals; Diabetes Mellitus -- Periodicals; Metabolic Diseases -- Periodicals; Diabète -- Périodiques; Métabolisme, Troubles du -- Périodiques; Endocrinologie -- Périodiques; Diabète -- Physiopathologie -- Périodiques; Diabetes; Metabolism -- Disorders; Electronic journals; Periodicals; 616.462
• DOI: 10.1016/j.dsx.2020.10.016
• Languages: English
• ISSNs: 1871-4021

Abstract

Abstract: Background and aims: This study investigated the clinical manifestations, outcomes and long-term complications of COVID-19 inpatients in southern part of Bangladesh while emphasizing on individuals having diabetes. Methods: A cross-sectional study was conducted for a sample of COVID-19 inpatients across four different hospitals of Bangladesh between April 1and June 30, 2020. Variation in clinical characteristics, contact history, comorbidities, treatment patterns, and immediate post COVID complications were investigated. Results: There were 734 COVID-19 presentations in this study of which 19.8% of patients had diabetes and 76% of the COVID-19 patients were male. Among biochemical parameters, plasma glucose, D-dimer, and Troponin-I levels were significantly elevated amidst the cohort with diabetes. The frequency of patients requiring insulin increased threefold during infection with SARS CoV-2. 1.4% patients developed new onset of diabetes mellitus. A number of COVID-19 patients with diabetes have been suffering from complications post-recovery including pain, discomfort, and sleep disturbance. Conclusion: Individuals with diabetes have experienced a severe manifestation of COVID-19 and post disease complications. Further in-depth studies focused on larger sample sizes are entailed to assess the relationships elaborately. Highlights: 19.87% of the total sample with COVID-19 had diabetes. New onset of diabetes was found in 1.35% of the COVID-19 recovered cases. Cases with diabetes were more symptomatic than those without. Pain and sleep disturbance were common complications among 30% recovered cases.