Biotech nanocellulose: A review on progress in product design and today's state of technical and medical applications. (15th February 2021)

• Record Type: Journal Article
• Authors: Klemm, Dieter; Petzold-Welcke, Katrin; Kramer, Friederike; Richter, Thomas; Raddatz, Vanessa; Fried, Wolfgang; Nietzsche, Sandor; Bellmann, Tom; Fischer, Dagmar
• Is Part Of: Carbohydrate polymers. Volume 254(2021)
• Publication Date: 2021-02-15
• Subjects: Bacterial nanocellulose -- Multilayered hydrogels -- Biotechnological design -- Medical implants -- Drug delivery -- Composites; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2020.117313
• Languages: English
• ISSNs: 0144-8617

Abstract

Highlights: A review on progress in product design of Biotech nanocellulose (BNC). Template-based production of multilayered tubes, membranes, composites and coatings. Process-controlled design of shape, surfaces and nanonetwork architecture. Groundbreaking application fields: medical implants and drug delivery systems. Potential of multilayered BNC for techniques such as electronics. Abstract: Biotech nanocellulose (bacterial nanocellulose, BNC) is a high potential natural polymer. Moreover, it is the only cellulose type that can be produced biotechnologically using microorganisms resulting in hydrogels with high purity, high mechanical strength and an interconnecting micropore system. Recently, the subject of intensive research is to influence this biosynthesis to create function-determining properties. This review reports on the progress in product design and today's state of technical and medical applications. A novel, dynamic, template-based technology, called Mobile Matrix Reservoir Technology (MMR Tech), is highlighted. Thereby, shape, dimensions, surface properties, and nanonetwork structures can be designed in a process-controlled manner. The formed multilayer materials open up new applications in medicine and technology. Especially medical materials for cardiovascular and visceral surgery, and drug delivery systems are developed. The effective production of layer-structured composites and coatings are important for potential applications in the electronics, paper, food and packaging technologies.