Differences in the subcellular distribution of cadmium and copper in the gills and liver of white sturgeon (Acipenser transmontanus) and rainbow trout (Oncorhynchus mykiss). (February 2021)

• Record Type: Journal Article
• Authors: Shekh, Kamran; Saeed, Huzaifa; Kodzhahinchev, Vladimir; Brinkmann, Markus; Hecker, Markus; Niyogi, Som
• Is Part Of: Chemosphere. Volume 265(2021)
• Publication Date: 2021-02
• Subjects: Subcellular distribution -- Accumulation -- Cadmium -- Copper -- Rainbow trout -- White sturgeon; Pollution -- Periodicals; Pollution -- Physiological effect -- Periodicals; Environmental sciences -- Periodicals; Atmospheric chemistry -- Periodicals; 551.511
• DOI: 10.1016/j.chemosphere.2020.129142
• Languages: English
• ISSNs: 0045-6535

Abstract

Abstract: Recent studies have shown that white sturgeon ( Acipenser transmontanus ) are more resistant to cadmium (Cd) compared to rainbow trout ( Oncorhynchus mykiss ), whereas they are more sensitive than rainbow trout when exposed to copper (Cu). Differences in the subcellular distribution of metals among species could be one of the factors responsible for the differences in the sensitivity to metals. Although, subcellular distribution has been studied extensively in many species with many metals, its direct role in species-specific differences in the sensitivity has not been well studied. The objective of this study was to evaluate the role of subcellular distribution of metals in species-specific differences in the sensitivity to metals between sturgeon and trout. We compared the subcellular distribution of metals Cd and Cu in the cellular debris, heat-stable proteins, heat-denatured fraction, metal-rich granules, and organelles fractions from the gills and liver after exposure of juveniles of both species to 1.25 and 20 μg/L Cd and Cu for 8 days, respectively. Sturgeon diverted a higher amount of Cd towards biologically inactive metal pool (BIM) and a lower amount towards the biologically active metal pool (BAM) compared to trout in both tissues. This explained why sturgeon are able to tolerate a relatively higher exposure level to Cd compared to trout. For Cu, there was no statistically significant species-specific differences in the amounts diverted towards either BAM or BIM; hence, white sturgeon's greater sensitivity to Cu was not explained by its subcellular distribution strategies. Graphical abstract: Image 1 Highlights: Mechanism of species-specific sensitivity of metals is not fully understood. Sturgeon diverted a higher amount of Cd towards biologically inactive metal pool. Subcellular distribution of Cu did not show any major species-specific differences.