Difficult-to-treat women for controlled ovarian hyperstimulation: tips and tricks. Issue 4 (July 2011)

• Record Type: Journal Article
• Authors: Artini, Paolo Giovanni; Papini, Francesca; Ruggiero, Maria; Scaravelli, Giulia; Di Berardino, Olga Maria; Simi, Giovanna; Cela, Vito
• Is Part Of: Expert review of endocrinology & metabolism. Volume 6:Issue 4(2011)
• Page Start: 617
• Page End: 627
• Publication Date: 2011-07
• Subjects: controlled ovarian hyperstimulation -- endometriosis -- in vitro fertilization -- polycystic ovary syndrome -- poor responder; Endocrinology -- Periodicals; Metabolism -- Periodicals; 616.4
• DOI: 10.1586/eem.11.43
• Languages: English
• ISSNs: 1744-6651

Abstract

The aim of this article is to clarify the different strategies used to induce controlled ovarian hyperstimulation in some groups of difficult-to-treat patients, namely poor-responder patients, polycystic ovarian patients and endometriosis patients. The success of in vitro fertilization depends on adequate follicle recruitment and the recovery of multiple good-quality oocytes by using controlled ovarian hyperstimulation. This is particularly difficult to achieve in patients with a high incidence of low ovarian response (stage III––IV endometriosis and premature ovarian failure patients) or an excessive ovarian response with a risk of ovarian hyperstimulation syndrome (polycystic ovary syndrome patients). Consequently, special methods are needed in these groups of patients in order to optimize in vitro fertilization results.