The real value of novel particulate carriers for sunscreen formulation. (October 2011)

• Record Type: Journal Article
• Authors: Blasi, Paolo; Schoubben, Aurélie; Giovagnoli, Stefano; Rossi, Carlo; Ricci, Maurizio
• Is Part Of: Expert review of dermatology. Volume 6:Number 5(2011)
• Page Start: 509
• Page End: 517
• Publication Date: 2011-10
• Subjects: cyclodextrins -- hydrotalcite-like compounds -- lipospheres -- photodegradation -- polymeric microparticles -- SLM -- solid lipid microparticles -- sunscreens; Dermatology -- Periodicals; 616.5005
• DOI: 10.1586/edm.11.57
• Languages: English
• ISSNs: 1746-9872

Abstract

Solar radiation is a consolidated environmental risk factor in the development of non-melanoma skin cancer and is responsible for sunburn and skin aging. By consequence, the use of sunscreen products is considered the best approach for skin protection. Today, sunscreen products are based on conventional formulations, such as creams, milks or gels, which do not protect chemical ultraviolet filters from photodegradation and allow their systemic absorption. In this article, innovative systems, namely clays, cyclodextrins, polymer and lipid microparticles, are discussed as potential sunscreen carriers to be embedded in the aforementioned formulations. Their capability to improve sunscreen performances, to reduce their potential toxicity issues and to overcome formulation problems are examined also.