Gold‐Catalyzed Oxidative Cross‐Coupling Reactions among Two Distinct Arenes and One Gold Carbene with Phosphoric Acids as Cocatalysts. Issue 24 (20th October 2020)

• Record Type: Journal Article
• Authors: Patil, Manoj D.; Kale, Balaji S.; Liu, Rai‐Shung
• Is Part Of: Advanced synthesis & catalysis. Volume 362:Issue 24(2020)
• Page Start: 5658
• Page End: 5668
• Publication Date: 2020-10-20
• Subjects: gold catalysis -- oxidative cross coupling -- gold carbenes -- α-aryl diazo compounds -- indoles -- anilines.; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202000879
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Gold‐catalyzed oxidative cross‐coupling reactions of two distinct arenes with one gold carbene furnish triarylmethane products. Notably, competitive homo‐coupling reactions are efficiently suppressed with a phosphoric acid as co‐catalyst (10 mol%) in THF. These cross‐coupling reactions have a wide scope of applicable substrates, with respect to indoles, arylamines, and α ‐aryl diazo cyanides or esters. Our mechanistic analysis indicates that the basicity of the arylanilines greatly affects the cross‐coupling efficiency. Abstract :