Hepatocellular Carcinoma: Acoustically Driven Microbubbles Enable Targeted Delivery of microRNA‐Loaded Nanoparticles to Spontaneous Hepatocellular Neoplasia in Canines (Adv. Therap. 12/2020). Issue 12 (18th December 2020)

• Record Type: Journal Article
• Authors: Kumar, Sukumar Uday; Telichko, Arsenii V.; Wang, Huaijun; Hyun, Dongwoon; Johnson, Eric G.; Kent, Michael S.; Rebhun, Robert B.; Dahl, Jeremy J.; Culp, William T. N.; Paulmurugan, Ramasamy
• Is Part Of: Advanced therapeutics. Volume 3:Issue 12(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-12-18
• Subjects: Therapeutics -- Periodicals; Pharmaceutical technology -- Periodicals; Pharmacogenetics -- Periodicals; 615.5
• DOI: 10.1002/adtp.202070027
• Languages: English
• ISSNs: 2366-3987

Abstract

Abstract : In article number 2000120, Jeremy J. Dahl, William T. N. Culp, Ramasamy Paulmurugan and co‐workers demonstrate a promising outcome from ultrasound assisted targeted delivery of therapeutic microRNAs loaded nanoparticles to spontaneous hepatocellular carcinoma in canines. This study lays the foundation for the safety and efficacy of this approach and the findings warrant a smooth transition to clinical trials.