Iron‐Catalyzed and Air‐Mediated C(sp3)−H Phosphorylation of 1, 3‐Dicarbonyl Compounds Involving C−C Bond Cleavage. Issue 24 (4th November 2020)

• Record Type: Journal Article
• Authors: Ou, Yingcong; Huang, Yuanting; Liu, Yu; Huo, Yanping; Gao, Yang; Li, Xianwei; Chen, Qian
• Is Part Of: Advanced synthesis & catalysis. Volume 362:Issue 24(2020)
• Page Start: 5783
• Page End: 5787
• Publication Date: 2020-11-04
• Subjects: Phosphorylation -- C(sp3)−H bonds -- iron catalysts -- air -- β-ketophosphine oxides; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202001020
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A C( sp 3 )−H phosphorylation has been achieved via the iron‐catalyzed cross‐coupling reactions between 1, 3‐dicarbonyl compounds and P(O)−H compounds involving C−C bond cleavages with air as the oxidant. This transformation provides a straightforward way to construct C( sp 3 )−P bonds, leading to the formation of β‐ketophosphine oxides in up to 93% yield with good functional group tolerance. Abstract :