Associations Between Salt‐Restriction Spoons and Long‐Term Changes in Urinary Na+/K+ Ratios and Blood Pressure: Findings From a Population‐Based Cohort. Issue 14 (21st July 2020)

• Record Type: Journal Article
• Authors: Hou, Lei; Guo, Xiaolei; Zhang, Jiyu; Chen, Xi; Yan, Liuxia; Cai, Xiaoning; Tang, Junli; Xu, Chunxiao; Wang, Baohua; Wu, Jing; Ma, Jixiang; Xu, Aiqiang
• Is Part Of: Journal of the American Heart Association. Volume 9:Issue 14(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-07-21
• Subjects: blood pressure -- cohort -- salt‐restriction spoon -- sodium intake; Heart -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; Cerebrovascular disease -- Periodicals; Cardiology -- Periodicals; 616.1
• DOI: 10.1161/JAHA.119.014897
• Languages: English
• ISSNs: 2047-9980

Abstract

Abstract : Background: There have been few studies on the relationship between long‐term changes in sodium intake and blood pressure. A method of reducing sodium intake in a population that is known for high‐sodium intake based on homemade cooking is also needed. Methods and Results: Our study was based on a baseline survey of 15 350 individuals aged 18 to 69 years with multistage random sampling and a 3‐year salt‐restriction campaign across Shandong Province, China. We included 339 individuals from six districts/counties in this cohort study, and the 24‐hour urinary sodium‐potassium ratio (Na + /K + ) served as an indicator of sodium intake. The average change in ratio was 2.39 (95% CI, 2.17–2.61) from 6.81 (95% CI, 6.41–7.21) at baseline to 4.41 (95% CI, 4.18–4.64) during the resurvey. Following a reduction from low to high quartiles of urinary Na + /K + ratio, the average increases were 10.9 (95% CI, 8.9–12.9), 9.2 (95% CI, 6.9–11.5), 6.3 (95% CI, 4.0–8.6), and 5.3 (95% CI, 2.9–7.7) mm Hg for systolic blood pressure ( P for trend=0.019) and 3.8 (95% CI, 2.4–5.2), 2.9 (95% CI, 1.7–4.2), 1.6 (95% CI, 0.4–2.8), and −0.3 (95% CI, −1.4–0.8) mm Hg for diastolic blood pressure ( P for trend=0.002), respectively. A reduction in salt intake was evident for people using a 2‐g salt‐restriction spoon for cooking (−3.49 versus −2.22; P =0.027) after adjustment of confounding factors, compared with nonusers. Similar findings were obtained for other salt‐restriction spoon–based indicators. Conclusions: Our study indicated that using a salt‐restriction spoon for cooking was associated with reduced salt intake that led to a blunting of blood pressure deterioration. This finding further supports the salt‐restriction spoon–based strategy for people whose primary salt intake is from homemade cooking.