Prevalence and Determinants of Vitamin D Deficiency in Children Aged 0–5 years in Jiangsu Province of China: A Cross-Sectional Multicenter Study. (29th May 2020)

• Record Type: Journal Article
• Authors: Zhao, Yan; Qin, Rui; Ma, Xianghua; Zhang, Xinhua; Hong, Hong; Lv, Heyu; Ye, Kan; Wei, Yarong; Zheng, Wen; Qi, Hongxia; Ni, Yufei; Zhang, Li; Yan, Juhua; Liu, Guoqin; Wu, Aiping
• Is Part Of: Current developments in nutrition. Volume 4(2020)Supplement 2
• Page Start: 1859
• Page End: 1859
• Publication Date: 2020-05-29
• Subjects: Nutrition -- Periodicals; Nutritional Physiological Phenomena; Nutrition; Periodicals; Periodicals; Fulltext; Internet Resources; Periodicals; 612.3
• DOI: 10.1093/cdn/nzaa067_086
• Languages: English
• ISSNs: 2475-2991

Abstract

Abstract: Objectives: To explore the vitamin D status and its related factors in infants and preschool. Methods: This was a large population-based multicenter study in which the representative children aged 0–5 years were recruited from 12 Children's Health Care Centers by a stratified cluster random-sampling method in 10 cities of Jiangsu Province, China. Kruskal-wallis test was used to describe median differences by continuous variables and chi-square test was used to examine differences in categorical variables. The associations between characteristics and risk factors with vitamin D deficiency and 25(OH)D level were used to evaluate by binary logistic regression and general linear model regression. Results: A total of 5289 children (2786 boys and 2503 girls) were investigated. The prevalence of deficiency vitamin D were 30.1%, The overall level of 25(OH)D was 64.0 (46.3 ∼ 83.0) nmol/ml. 0–5 year old children with higher odds of vitamin D deficiency and lower 25(OH)D level were more likely to be at older age, girls, survey in spring, location in southern of Jiangsu province, preference for meat and sweets, meat intake > 150.0 g/d, time of sleeping < 10 h/d and outdoor activity < 2 h/d (all P < 0.05). However, those with lower odds of vitamin D deficiency and higher 25(OH)D level were more likely to be the number of parity≥ 2 times, milk intake ≥ 250 ml/d, vitamin D supplementation from birth to 6 months, the initial time of vitamin D supplementation after birth ≤ 1 months, vitamin D supplementation and calcium supplementation in the last 3 months, and daily dose of vitamin D supplementation > 400 IU (all P < 0.05). Conclusions: Most 0–5 year old children in Jiangsu province have poor vitamin D levels. The 25(OH)D levels and vitamin D deficiency were associated with age, gender, parity, season of survey, region of residence, daily intake of milk, meat, vitamin D and calcium supplementation, the initial time of vitamin D supplementation after birth, preference for eating meat and sweets, time of sleeping and outdoor activity every day for children. Funding Sources: This work was funded by the construction fund for key subjects of women and children of Jiangsu Province (FXK201203).