Orofacial dyskinesia post resection of pineal gland tumor. Issue 12 (26th December 2020)

• Record Type: Journal Article
• Authors: Yazbeck, Mohamad; Dabboucy, Baraa; Comair, Youssef
• Is Part Of: Journal of surgical case reports. Volume 2020:Issue 12(2020)
• Publication Date: 2020-12-26
• Subjects: Surgery -- Periodicals; Surgery -- Case studies -- Periodicals; 617.005
• DOI: 10.1093/jscr/rjaa465
• Languages: English
• ISSNs: 2042-8812

Abstract

Abstract: We reported a case of a 33-year-old lady who was diagnosed with a Pineal tumor and underwent craniotomy and gross total surgical resection of the mass through a right occipital transtentorial approach. Immediately upon extubation, the patient started to have persistent chewing-like movements typical of orofacial dyskinesia that resulted later in buccal mucosal injury and swelling of the lips. The movements spontaneously resolved after 3 days. The patient was not taking any medications that were known to induce such movements. Literature review showed that one of the possible mechanisms could be that the suddenly reduced melatonin level in the acute postoperative period leads to dysregulation of dopamine secretion in the nigrostriatal and limbic system causing these abnormal movements. To the best of our knowledge, this is the first such reported complication of orofacial dyskinesia post craniotomy for resection of the pineal tumor in humans.