A NOVEL NONPEPTIDE CGRP RECEPTOR ANTAGONIST, �COMPOUND 1� (WO98/11128) IS A HIGH AFFINITY COMPETITIVE ANTAGONIST AT THE CGRP1 RECEPTOR IN HUMAN CORONARY ARTERIES. (2001)

• Record Type: Journal Article
• Authors: Hasbak Hasbak, P. P.; Opgaard Opgaard, O. Saetrum O. Saetrum; Eskesen Eskesen, K. K.; Schifter Schifter, S. S.; Arendrup Arendrup, H. H.; Longmore Longmore, J. J.; Edvinsson Edvinsson, L. L.
• Is Part Of: TheScientificWorldjournal. Volume 1(2001)
• Page Start: 33
• Page End: 33
• Publication Date: 2001
• Subjects: Science -- Periodicals; Technology -- Periodicals; Medicine -- Periodicals; 505
• DOI: 10.1100/tsw.2001.416
• Languages: English
• ISSNs: 2356-6140

Abstract

Abstract : Functional CGRP and adrenomedullin receptors appear to consist of at least three different kinds of proteins: the calcitonin receptor-like receptor (CRLR), receptor-activity-modifying protein (RAMPs), and the receptor component protein (RCP) that couples the receptor to the cellular signal transduction pathway.