ESIPT Coupled RAHB Probe for Estimation of Cyanide in Human Blood Serum/Plasma like Solutions Using Chemodosimetric Approach. Issue 2 (18th January 2017)

• Record Type: Journal Article
• Authors: Gupta, Akul Sen; Paul, Kamaldeep; Luxami, Vijay
• Is Part Of: ChemistrySelect. Volume 2:Issue 2(2017)
• Page Start: 800
• Page End: 804
• Publication Date: 2017-01-18
• Subjects: Benzimidazole -- Chemodosimeter -- Cyanide sensor -- DFT -- Human blood serum; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201601687
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: Benzimidazole based probe 2 has been synthesized that exhibits both RAHBs and ESIPT phenomenons on single platform. Probe 2 is used for selective estimation of CN − ions. The chemodosimetric approach is successfully used for estimation of CN − ions (100 nM) in human blood sample and plasma like solutions. The interaction behaviour of CN − with probe 2 has been confirmed through NMR titrations as well as DFT calculations. Abstract : Benzimidazole based probe 2 has been synthesized that exhibits both RAHBs and ESIPT phenomenon on single platform for the estimation of CN − ions. The chemodosimetric approach is successfully used to detect CN − ions in plasma like solutions as well as human blood serum. The interaction behaviour of CN − with probe 2 has been confirmed through NMR titrations as well as DFT calculations.