A new fusicoccane diterpene and a new polyene from the plant endophytic fungus Talaromyces pinophilus and their antimicrobial activities. Issue 1 (2nd January 2021)

• Record Type: Journal Article
• Authors: Zhao, Wen-Ting; Shi, Xiong; Xian, Peng-Jie; Feng, Zhang; Yang, Jian; Yang, Xiao-Long
• Is Part Of: Natural product research. Volume 35:Issue 1(2021)
• Page Start: 124
• Page End: 130
• Publication Date: 2021-01-02
• Subjects: Salvia miltiorrhiza -- Talaromyces pinophilus -- fusicoccane diterpene -- polyene -- antimicrobial activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1616727
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new fusicoccane diterpene, pinophicin A (1), and a new polyene, pinophol A (2 ), were isolated from the plant endophytic fungus Talaromyces pinophilus obtained from the aerial parts of Salvia miltiorrhiza . The structures and relative configurations of 1 –2 were determined by the analysis of extensive spectroscopic data, chemical method, and comparison with known compounds. Compound 2 exhibited weak antibacterial activity against Bacterium paratyphosum B with an MIC value of 50 μg/mL. Graphical Abstract: