Development of affinity between target analytes and substrates in surface enhanced Raman spectroscopy for environmental pollutant detection. Issue 47 (23rd November 2020)

• Record Type: Journal Article
• Authors: Wang, Shiqiang; Sun, Bing; Feng, Junjie; An, Fei; Li, Na; Wang, Haozhi; Tian, Mingwei
• Is Part Of: Analytical methods. Volume 12:Issue 47(2020)
• Page Start: 5657
• Page End: 5670
• Publication Date: 2020-11-23
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/d0ay01760d
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : Different affinities to immobilize target molecules onto the surface of SERS substrates. Abstract : Environmental pollution has long been a social concern due to the variety of pollutants and their wide distribution, persistence and being detrimental to health. It is therefore necessary to develop rapid and sensitive strategies to trace and detect these compounds. Among various detection methodologies, surface enhanced Raman spectroscopy (SERS) has become an attractive option as it enables accurate analyte identification, simple sample preparation, rapid detection and ultra-high sensitivity without any interference from water. For SERS detection, an essential yet challenging step is the effective capture of target analytes onto the surface of metal nanostructures with a high intensity of enhanced electromagnetic field. This review has systematically summarized recent advances in developing affinity between targets and the surface of SERS substrates via direct adsorption, hydrophobic functional groups, boronate affinity, metal organic frameworks (MOFs), DNA aptamers and molecularly imprinted polymers (MIPs). At the end of this review, technical limitations and outlook have been provided, with suggestions on optimizing SERS techniques for real-world applications in environmental pollutant detection.