Inflammation of a Posterior Ciliary Artery in a Naive Cynomolgus Macaque. (April 2021)

• Record Type: Journal Article
• Authors: Laing, Steven T.; Bockenstedt, Marie M.; Booler, Helen S.
• Other Names: Ramos Meg Ferrell guest-editor.; Schafer Kenneth guest-editor.; Sorden Steven guest-editor.
• Is Part Of: Toxicologic pathology. Volume 49:Number 3(2021)
• Page Start: 602
• Page End: 604
• Publication Date: 2021-04
• Subjects: vascular system -- nonhuman primate pathology -- cardiovascular system -- background lesions; Pathology -- Periodicals; Toxicology -- Periodicals; Pathology; Toxicology; 615.9
• DOI: 10.1177/0192623320952337
• Languages: English
• ISSNs: 0192-6233

Abstract

This brief communication describes a previously unreported background lesion in the eye of a naive cynomolgus macaque. Inflammation of a posterior ciliary artery was, in this case, morphologically similar to vascular inflammation of other tissues described in naive cynomolgus macaques. However, the available literature does not describe this lesion at this anatomical site. The affected animal did not present with any abnormal clinical signs and ophthalmological examinations were within normal limits. Toxicologic pathologists should be aware of this finding in order to help differentiate it from a test item–related finding.