A validation study for remote testing of cognitive function in multiple sclerosis. (April 2021)

• Record Type: Journal Article
• Authors: Barcellos, Lisa F; Horton, Mary; Shao, Xiaorong; Bellesis, Kalliope H; Chinn, Terrence; Waubant, Emmanuelle; Bakshi, Nandini; Marcus, Jackie; Benedict, Ralph HB; Schaefer, Catherine
• Is Part Of: Multiple sclerosis. Volume 27:Number 5(2021)
• Page Start: 795
• Page End: 798
• Publication Date: 2021-04
• Subjects: Multiple sclerosis -- cognitive impairment -- CVLT-II -- SDMT; Central nervous system -- Diseases -- Periodicals; Myelin sheath -- Diseases -- Periodicals; Inflammation -- Periodicals; Multiple sclerosis -- Periodicals; Central Nervous System Diseases -- Periodicals; Demyelinating Diseases -- Periodicals; Inflammation -- Periodicals; Multiple Sclerosis -- Periodicals; Système nerveux central -- Maladies -- Périodiques; Gaine de myéline -- Maladies -- Périodiques; Inflammation (Pathologie) -- Périodiques; Sclérose en plaques -- Périodiques; Electronic journals; 616.834005
• DOI: 10.1177/1352458520937385
• Languages: English
• ISSNs: 1352-4585

Abstract

Objectives: Determine the validity and reliability of a remote, technician-guided cognitive assessment for multiple sclerosis (MS), incorporating the Symbol Digit Modalities Test (SDMT) and the California Verbal Learning Test, Second Edition (CVLT-II). Methods: In 100 patients, we compared conventional in-person testing to remote, web-assisted assessments, and in 36 patients, we assessed test–retest reliability using two equivalent, alternative forms. Results: In-person and remote-administered SDMT ( r = 0.85) and CVLT-II ( r = 0.71) results were very similar. Reliability was adequate and alternative forms of SDMT ( r = 0.92) and CVLT-II ( r = 0.81) produced similar results. Conclusions: Findings indicate remote assessment can provide valid, reliable measures of cognitive function in MS.