Abstract : A new series derived from 4‐(2‐chloroacetyl)‐1, 2‐dihydro‐2, 3‐dimethyl‐1‐phenylpyrazol‐5‐one was synthesized and characterized, and its pharmacological activity toward α‐glucosidase and α‐amylase enzyme inhibition was screened. Moreover, molecular docking studies were conducted to support the findings. Abstract :