Cardiovascular and Cerebrovascular Mortality Associated With Acute Exposure to PM2.5 in Mexico City. Issue 7 (July 2018)

• Record Type: Journal Article
• Authors: Gutiérrez-Avila, Iván; Rojas-Bracho, Leonora; Riojas-Rodríguez, Horacio; Kloog, Itai; Just, Allan C.; Rothenberg, Stephen J.
• Is Part Of: Stroke. Volume 49:Issue 7(2018)
• Publication Date: 2018-07
• Subjects: cardiovascular mortality -- particulate matter -- stroke; Cerebrovascular disease -- Periodicals; Cerebral circulation -- Periodicals; 616.81
• DOI: 10.1161/STROKEAHA.118.021034
• Languages: English
• ISSNs: 0039-2499

Abstract

Abstract : Background and Purpose—: Acute exposure to particulate matter with aerodynamic diameter <2.5 μm (PM2.5 ) is associated with acute cardiovascular and cerebrovascular mortality. The aim of this study was to evaluate these associations with specific causes of cardiovascular and cerebrovascular mortality in Mexico City. Methods—: We obtained daily mortality records for Mexico City from 2004 to 2013 for cardiovascular and cerebrovascular causes in people ≥25 and ≥65 years old. Exposure to PM2.5 was assessed with daily estimates from a new hybrid spatiotemporal model using satellite measurements of aerosol optical depth PM2.5 and compared to ground level PM2.5 measurements with missing data estimated with generalized additive models PM2.5 . We fitted Poisson regression models with distributed lags for all mortality outcomes. Results—: An increase of 10 µg/m 3 in aerosol optical depth PM2.5 was associated with increased cardiovascular (1.22%; 95% confidence interval, 0.17–2.28) and cerebrovascular mortality (3.43%; 95% confidence interval, 0.10–6.28) for lag days 0 to 1 (lag 0–1). Stronger effects were identified for hemorrhagic stroke and people ≥65 years. Associations were slightly smaller using generalized additive models PM2.5 . Conclusions—: These results support the evidence that acute exposure to PM2.5 is associated with increased risk of specific cardiovascular and cerebrovascular mortality causes. Abstract : Supplemental Digital Content is available in the text.