A Cluster of Cefepime-induced Neutropenia During Outpatient Parenteral Antimicrobial Therapy. (11th February 2019)

• Record Type: Journal Article
• Authors: Foong, Kap Sum; Hsueh, Kevin; Bailey, Thomas C; Luong, Lan; Iqbal, Ayesha; Hoehner, Christine; Connor, Lee; Casabar, Ed; Lane, Michael; Burnett, Yvonne; Ritchie, David; Krekel, Tamara; Newland, Helen; Weilmuenster, Lori; Heuring, Brett; Durkin, Michael J; Hamad, Yasir
• Is Part Of: Clinical infectious diseases. Volume 69:Number 3(2019)
• Page Start: 534
• Page End: 537
• Publication Date: 2019-02-11
• Subjects: cefepime -- cefepime-induced neutropenia -- drug-induced neutropenia -- adverse drug event -- OPAT; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciy1112
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: A cluster of cefepime-induced neutropenia (CIN) was identified from June 2017 to May 2018 in a regional outpatient parenteral antimicrobial therapy population. Our data suggest prolonged courses of cefepime (≥2 weeks), administered by rapid intravenous push, were associated with a higher risk of CIN.