Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide. (12th December 2020)

• Record Type: Journal Article
• Authors: Vaxman, Iuliana; Eaton, John; Lee, Hee Eun; Gertz, Morie A.
• Other Names: Grenda Ryszard Academic Editor.
• Is Part Of: Case reports in transplantation. Volume 2020(2020)
• Publication Date: 2020-12-12
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; Transplantation; Transplantation of organs, tissues, etc; Periodicals; Periodicals; 617.954
• DOI: 10.1155/2020/8894922
• Languages: English
• ISSNs: 2090-6943

Abstract

Abstract : Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection. The patient recovered after treatment with corticosteroids, resumption of mycophenolate mofetil, and cessation of lenalidomide. Lenalidomide-associated allograft rejection has been reported in other organs. However, this is the first case report of liver rejection induced by lenalidomide.