Lipidomics and Anti-Inflammation Activity of Brown Algae, Lobophora sp., in Vietnam. (9th December 2020)

• Record Type: Journal Article
• Authors: Pham, Thu Hue; Nguyen, Van Tuyen Anh; Do, Thi Thanh Trung; Do, Anh Duy; Dam, Duc Tien; Tran, Thi Thanh Van; Pham, Quoc Long; Le, Tat Thanh
• Other Names: Mastinu Andrea Academic Editor.
• Is Part Of: Journal of chemistry. Volume 2020(2020)
• Publication Date: 2020-12-09
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1155/2020/8829054
• Languages: English
• ISSNs: 2090-9063

Abstract

Abstract : Lobophora sp., belonging to brown macro algae phylum, is found in coral reefs. In this study, the fatty acid composition, lipid classes, polar lipid molecular forms, and bioactivities of this algae have been determined. It follows that five classes including polar lipid (Pol), sterol (ST), free fatty acids (FFA), triacylglycerol (TAG), and hydrocarbon and wax (HW), 23 fatty acids containing 5 PUFAs (ALA, GLA, AA, EPA, and DHA) and 157 molecular types of polar lipid group containing 48 phospholipid molecular forms belonging to 4 subclasses (PI (11), PC (14), PG (22), PA (1)), 45 glycolipid molecular forms classified into 3 subclasses of MGDG (8), DGDG (1), SQDG (36), and 64 betaine lipid molecular forms belonging to 2 subclasses (DGTA (37), DGTS (27)) have been identified for the first time from this algae. Furthermore, both polar lipid (PL) and unpolar lipid (UPL) show the NO inhibition activities with values of IC50 ranging from 52.10 to 66.21 µ g/mL. Thus, lipid of this brown algae could promise to be a potential source for application in food, cosmetic, and pharmaceutic industry.