The impact of cardiac troponin in elderly patients in the absence of acute coronary syndrome: A systematic review. (December 2020)

• Record Type: Journal Article
• Authors: Sedighi, Seyed Mahdi; Nguyen, Michel; Khalil, Abdelouahed; Fülöp, Tamas
• Is Part Of: IJC heart & vasculature. Volume 31(2021)
• Publication Date: 2020-12
• Subjects: Cardiac troponin -- Elderly patients without acute coronary syndrome -- Chronic diseases; Cardiovascular system -- Diseases -- Periodicals; Cardiovascular system -- Pathophysiology -- Periodicals; 616.1005
• DOI: 10.1016/j.ijcha.2020.100629
• Languages: English
• ISSNs: 2352-9067

Abstract

Abstract: Comorbidities are common risk factors for rising cardiac troponin in non-acute coronary syndromes conditions. Furthermore, the risk for all-cause mortality appears to be correlated to the troponin levels. Consequently, measurement of cardiac troponin in hospital admission may contribute to predict the mortality risk in elderly patients. Among geriatric patients without acute coronary syndrome, with concomitant diseases, the correct interpretation of elevated cardiac troponin, particularly in emergency conditions poses a diagnostic dilemma. Although in several studies it is suggested that at the presence of comorbidity, there is an increase in cardiac troponin values, the elderly patients have not been included conclusively. In order to assess the diagnostic and prognostic role of cardiac troponin elevation in geriatric patients suffering from chronic diseases, a systematic review was performed. The study included the elderly patients free of acute coronary syndrome admitted to the hospital with concomitant disease, with a report of at least one cardiac troponin measurement. We found that elevated cardiac troponin is an independent prognostic factor, predicting all-cause morbidity and mortality burden in geriatric patients without acute coronary syndromes.