The European Joint Research Project UHDpulse – Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates. (December 2020)

• Record Type: Journal Article
• Authors: Schüller, Andreas; Heinrich, Sophie; Fouillade, Charles; Subiel, Anna; De Marzi, Ludovic; Romano, Francesco; Peier, Peter; Trachsel, Maria; Fleta, Celeste; Kranzer, Rafael; Caresana, Marco; Salvador, Samuel; Busold, Simon; Schönfeld, Andreas; McEwen, Malcolm; Gomez, Faustino; Solc, Jaroslav; Bailat, Claude; Linhart, Vladimir; Jakubek, Jan; Pawelke, Jörg; Borghesi, Marco; Kapsch, Ralf-Peter; Knyziak, Adrian; Boso, Alberto; Olsovcova, Veronika; Kottler, Christian; Poppinga, Daniela; Ambrozova, Iva; Schmitzer, Claus-Stefan; Rossomme, Severine; Vozenin, Marie-Catherine;
• Is Part Of: Physica medica. Volume 80(2021)
• Page Start: 134
• Page End: 150
• Publication Date: 2020-12
• Subjects: Dosimetry -- FLASH beams -- Absorbed dose -- Traceability -- High dose rates -- European metrology project; Medical physics -- Periodicals; Biophysics -- Periodicals; Biophysics -- Periodicals; Imagerie médicale -- Périodiques; Radiothérapie -- Périodiques; Rayons X -- Sécurité -- Mesures -- Périodiques; Physique -- Périodiques; Médecine -- Périodiques; 610.153
• DOI: 10.1016/j.ejmp.2020.09.020
• Languages: English
• ISSNs: 1120-1797

Abstract

Highlights: Ultra-high dose rate reduces adverse side effects in radiotherapy (FLASH effect). Studies and implementation in practice requires accurate dose measurements. An European joint research project was started to develop a measurement framework. Tools for dosimetry of ultra-high pulse dose rate beams will be provided. Abstract: UHDpulse – Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates is a recently started European Joint Research Project with the aim to develop and improve dosimetry standards for FLASH radiotherapy, very high energy electron (VHEE) radiotherapy and laser-driven medical accelerators. This paper gives a short overview about the current state of developments of radiotherapy with FLASH electrons and protons, very high energy electrons as well as laser-driven particles and the related challenges in dosimetry due to the ultra-high dose rate during the short radiation pulses. We summarize the objectives and plans of the UHDpulse project and present the 16 participating partners.