An assessment of physician reasons for prescribing Insulin Lispro 200 units/ml in Germany. Issue 8 (16th November 2020)

• Record Type: Journal Article
• Authors: Chen, Jieling; Perez-Nieves, Magaly; Piras De Oliveira, Carolina; Spaepen, Erik; Osumili, Beatrice; Poon, Jiat-Ling; Schloot, Nanette; Lara, Nuria; Garcia Alvarez, Laura; Roset, Montserrat
• Is Part Of: Postgraduate medicine. Volume 132:Issue 8(2020)
• Page Start: 727
• Page End: 736
• Publication Date: 2020-11-16
• Subjects: Concentrated insulin -- diabetes mellitus -- injection burden -- Insulin Lispro 200 units/ml -- mealtime insulin -- physician survey; Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610.5
• DOI: 10.1080/00325481.2020.1805968
• Languages: English
• ISSNs: 0032-5481

Abstract

ABSTRACT: Objective: To understand physicians' reasons for prescribing Insulin Lispro 200 units/ml (IL200) and their experience with IL200 treatment in Germany. Methods: The survey consisted of 28 questions on physician's profile, average IL200 patients' characteristics and rationales for prescribing IL200. Questions were rated on a scale of 0 ('not at all important'/'strongly disagree') to 4 ('absolutely important'/'strongly agree'). Results: The surveyed physicians had a mean (SD) experience of 18.1 (7.0) years managing diabetes, consulted an average of 226.8 patients with diabetes/month and prescribed IL200 to 56.1% of their patients on mealtime insulin (MTI). About 80.0% of IL200 patients had type 2 diabetes mellitus, were overweight/obese, and received >20 units/day of MTI. More than 70.0% of physicians rated patient's insulin dose, pattern of self-measured glucose levels, hemoglobin A1c (HbA1c) (clinical); adherence, hypoglycemia knowledge, motivation to improve lifestyle, desire to reduce injection volume and emotional struggle with controlling HbA1c (behavioral) as 'very important'/'absolutely important' factors when prescribing IL200. Conclusion: Physicians considered IL200 a promising treatment option that reduces the injection burden for patients on MTI. Physicians adopted a patient-centered perspective by aligning IL200 prescribing decisions with each patient's medical needs and non-clinical preferences, with an aim to encourage treatment adherence through resorting to IL200's advantageous attributes.