Booming Omics in Schistosoma. Issue 1 (January 2021)

• Record Type: Journal Article
• Authors: Le Govic, Yohann; Gourbal, Benjamin; Boissier, Jérôme
• Is Part Of: Trends in parasitology. Volume 37:Issue 1(2021)
• Page Start: 6
• Page End: 8
• Publication Date: 2021-01
• Subjects: schistosomiasis -- RNA interference -- scRNA-seq -- praziquantel -- proteasome -- blood feeding; Parasitology -- Periodicals; Parasitology -- Periodicals; Biology -- Periodicals; Parasitology; Biology; Parasitologie -- Périodiques; Online resources; 571.999
• DOI: 10.1016/j.pt.2020.10.010
• Languages: English
• ISSNs: 1471-4922

Abstract

Abstract : Efforts to eliminate schistosomiasis are hindered by incomplete efficacy of the only FDA-approved antischistosomal drug, praziquantel. By using postgenomic technologies, Wendt et al . and Wang et al . deciphered the function of several genes required for worm survival and pathogenesis, which opens the way for the development of innovative parasite-targeted therapies.