18F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET. (November 2020)

• Record Type: Journal Article
• Authors: Watabe, Tadashi; Shimamoto, Hiroaki; Naka, Sadahiro; Kamiya, Takashi; Murakami, Shumei
• Is Part Of: Clinical nuclear medicine. Volume 45:Number 11(2020)
• Publication Date: 2020-11
• Subjects: 18F-FBPA -- 18F-FDG -- sarcoidosis; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003274
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 68-year-old man with sarcoidosis showed high 18 F-FDG uptake in the mediastinal and hilar lymph nodes on 18 F-FDG PET, suggesting active inflammation. 18 F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specificity as a substrate of L-type amino acid transporter 1. 18 F-fluoro-boronophenylalanine PET can be used for precise evaluation in oncology when the differentiation between inflammation and metastasis is inconclusive on 18 F-FDG PET.