Clinical Sensitivity of Severe Acute Respiratory Syndrome Coronavirus 2 Nucleic Acid Amplification Tests for Diagnosing Coronavirus Disease 2019. (24th July 2020)

• Record Type: Journal Article
• Authors: Ridgway, Jessica P; Pisano, Jennifer; Landon, Emily; Beavis, Kathleen G; Robicsek, Ari
• Is Part Of: Open forum infectious diseases. Volume 7:Number 8(2020)
• Publication Date: 2020-07-24
• Subjects: COVID-19 -- SARS-CoV-2; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa315
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Utilizing 34 348 severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) nucleic acid amplification test (NAAT) results from 2 health systems, we estimated the clinical sensitivity of a single SARS-CoV-2 NAAT. We found that SARS-CoV-2 NAAT has 82%–97% sensitivity for diagnosing coronavirus disease 2019 among symptomatic patients. Abstract : Using severe acute respiratory syndrome coronavirus2 (SARS-CoV-2) nucleic acid amplification test (NAAT) results from two large health systems, this study estimated the clinical sensitivity of a single SARS-CoV-2 NAAT to be 82-97% for diagnosing COVID-19 among symptomatic patients.