Association between serum vitamin D and depressive symptoms in apparently healthy male adults undergoing routine health check-ups at a single centre. Issue 14 (2nd October 2020)

• Record Type: Journal Article
• Authors: Kim, Sung Hoon; Lee, Hae Jeong; Chae, Chang Ho; Park, Seung Hyun; Son, Jun Seok
• Is Part Of: Public health nutrition. Volume 23:Issue 14(2020)
• Page Start: 2530
• Page End: 2538
• Publication Date: 2020-10-02
• Subjects: Vitamin D, -- Depression, -- Male adult, -- Routine health check-ups; Nutrition -- Periodicals; Nutrition policy -- Periodicals; Public health -- Periodicals; 613.2
• DOI: 10.1017/S1368980020000592
• Languages: English
• ISSNs: 1368-9800

Abstract

Abstract: Objective: To determine the level of vitamin D and to identify the association between vitamin D and depressive symptoms in apparently healthy Korean male adults. Design: A retrospective study design. Among 43 513 participants between 1 March and 30 November 2018, after eliminating participants with a history of depression or vitamin D deficiency, 9058 were included. To determine the level of vitamin D, serum 25-hydroxyvitamin D [25(OH)D] was measured. To assess the level of depression, the Korean version of the Center for Epidemiologic Studies Depression Scale (CES-D) was used. Setting: South Korea. Participants: Male adults who underwent routine health check-ups. Results: The average vitamin D level was 22·31 ± 7·09 ng/ml as 25(OH)D, while the number of subjects in the vitamin D insufficiency group with a finding of <20 ng/ml was 3783 (41·8 %). The mean CES-D score in all subjects was 8·31 ± 5·97 points, and the proportion of the depressive symptoms group with a score of ≥16 was 8·71 %. The OR of patients in the depressive symptoms group also being in the insufficiency group was found to be 1·49 (95 % CI 1·12, 2·00). Conclusions: A total of 41·8 % of apparently healthy male adults had vitamin D levels <20 ng/ml. We identified an association between vitamin D insufficiency and depressive symptoms in apparently healthy Korean male adults.