Changes in dietary inflammatory potential predict changes in sleep quality metrics, but not sleep duration. Issue 11 (14th May 2020)

• Record Type: Journal Article
• Authors: Wirth, Michael D; Jessup, Angela; Turner-McGrievy, Gabrielle; Shivappa, Nitin; Hurley, Thomas G; Hébert, James R
• Is Part Of: Sleep. Volume 43:Issue 11(2020)
• Publication Date: 2020-05-14
• Subjects: inflammation -- diet -- Dietary Inflammatory Index -- objective sleep -- wake-after-sleep-onset -- sleep efficiency; Sleep -- Physiological aspects -- Periodicals; Sleep disorders -- Periodicals; Sommeil -- Aspect physiologique -- Périodiques; Sommeil, Troubles du -- Périodiques; Sleep disorders; Sleep -- Physiological aspects; Sleep -- physiological aspects; Sleep Wake Disorders; Psychophysiology; Electronic journals; Periodicals; 616.8498
• DOI: 10.1093/sleep/zsaa093
• Languages: English
• ISSNs: 0161-8105

Abstract

Abstract: Study Objectives: Non-pharmacological sleep interventions may improve sleep profiles without the side-effects observed with many pharmacological sleep aids. The objective of this research was to examine the association between sleep and inflammation and to examine how changes in dietary inflammatory potential influence changes in sleep. Methods: The Inflammation Management Intervention Study (IMAGINE), which was a dietary intervention designed to lower inflammation, provided access to 24-h dietary recalls (24HR), objectively measured sleep using Sensewear TM armbands, and a range of self-reported demographics, health histories, lifestyle behaviors, psychosocial metrics, anthropometric measurements, and inflammatory biomarkers. Dietary Inflammatory Index ® (DII ® ) scores were calculated from three unannounced 24HR-derived estimated intakes of whole foods and micro and macronutrients over a 2-week period at baseline and post-intervention (i.e. month 3). Statistical analyses primarily utilized linear regression. Results: At baseline, for every 1-min increase in sleep onset latency, tumor necrosis factor-α increased by 0.015 pg/mL (±0.008, p = 0.05). Every one-percentage increase in sleep efficiency was associated with decreased C-reactive protein (CRP) of −0.088 mg/L (±0.032, p = 0.01). Every 1-min increase in wake-after-sleep-onset (WASO) increased both CRP and interleukin-6. Compared to participants with pro-inflammatory DII changes over 3 months, those with anti-inflammatory changes decreased WASO (0 vs. −25 min, respectively, p < 0.01) and improved sleep efficiency (−2.1% vs. +2.6%, respectively, p = 0.04). Conclusions: Non-pharmacological treatments, such as anti-inflammatory diets, may improve sleep in some adults. Future research involving dietary treatments to improve sleep should not only focus on the general population, but also in those commonly experiencing co-morbid sleep complaints. Clinical Trial Information: NCT02382458.