Crossing the Cervicothoracic Junction During Posterior Cervical Fusion for Myelopathy Is Associated With Superior Radiographic Parameters But Similar Clinical Outcomes. Issue 5 (23rd June 2020)

• Record Type: Journal Article
• Authors: Chan, Andrew K; Badiee, Ryan K; Rivera, Joshua; Chang, Chih-Chang; Robinson, Leslie C; Mehra, Ratnesh N; Tan, Lee A; Clark, Aaron J; Dhall, Sanjay S; Chou, Dean; Mummaneni, Praveen V
• Is Part Of: Neurosurgery. Volume 87:Issue 5(2020)
• Page Start: 1016
• Page End: 1024
• Publication Date: 2020-06-23
• Subjects: Cervical spondylotic myelopathy -- Posterior cervical laminectomy and fusion -- Cervicothoracic junction -- Neck pain -- Cervical lordosis -- Cervical radiographic parameters; Nervous system -- Surgery -- Periodicals; 617.48005
• DOI: 10.1093/neuros/nyaa241
• Languages: English
• ISSNs: 0148-396X

Abstract

Abstract: Background: For laminectomy and posterior spinal fusion (LPSF) surgery for cervical spondylotic myelopathy (CSM), the evidence is unclear as to whether fusions should cross the cervicothoracic junction (CTJ). Objective: To compare LPSF outcomes between those with and without lower instrumented vertebrae (LIV) crossing the CTJ. Methods: A consecutive series of adults undergoing LPSF for CSM from 2012 to 2018 with a minimum of 12-mo follow-up were identified. LPSF with subaxial upper instrumented vertebrae and LIV between C6 and T2 were included. Clinical and radiographic outcomes were compared. Results: A total of 79 patients were included: 46 crossed the CTJ (crossed-CTJ) and 33 did not. The mean follow-up was 22.2 mo (minimum: 12 mo). Crossed-CTJ had higher preoperative C2-7 sagittal vertical axis (cSVA) (33.3 ± 16.0 vs 23.8 ± 12.4 mm, P = .01) but similar preoperative cervical lordosis (CL) and CL minus T1-slope (CL minus T1-slope) ( P > .05, both comparisons). The overall reoperation rate was 3.8% (crossed-CTJ: 2.2% vs not-crossed: 6.1%, P = .37). In adjusted analyses, crossed-CTJ was associated with superior cSVA (β = –9.7; P = .002), CL (β = 6.2; P = .04), and CL minus T1-slope (β = –6.6; P = .04), but longer operative times (β = 46.3; P = .001). Crossed- and not-crossed CTJ achieved similar postoperative patient-reported outcomes [Visual Analog Scale (VAS) neck pain, VAS arm pain, Nurick Grade, Modified Japanese Orthopedic Association Scale, Neck Disability Index, and EuroQol-5D] in adjusted multivariable analyses (adjusted P > .05). For the entire cohort, higher postoperative CL was associated with lower postoperative arm pain (adjusted Pearson's r –0.1, P = .02). No postoperative cervical radiographic parameters were associated with neck pain ( P > .05). Conclusion: Subaxial LPSF for CSM that crossed the CTJ were associated with superior radiographic outcomes for cSVA, CL, and CL minus T1-slope, but longer operative times. There were no differences in neck pain or reoperation rate. Graphical Abstract: