Does Rotavirus Vaccination Affect Longer-Term Intussusception Risk in US Infants?. (14th June 2019)

• Record Type: Journal Article
• Authors: Burke, Rachel M; Tate, Jacqueline E; Dahl, Rebecca M; Aliabadi, Negar; Parashar, Umesh D
• Is Part Of: Journal of the Pediatric Infectious Diseases Society. Volume 9:Number 2(2020)
• Page Start: 257
• Page End: 260
• Publication Date: 2019-06-14
• Subjects: immunizations -- intussusception -- pediatric gastroenteritis -- rotavirus -- rotavirus vaccine; Communicable diseases in children -- Periodicals; Children -- Diseases -- Periodicals; 618.929
• DOI: 10.1093/jpids/piz035
• Languages: English
• ISSNs: 2048-7193

Abstract

Abstract: Rotavirus vaccination has been associated with a short-term increased risk of intussusception. Our analysis of insurance claims for 1 858 827 US children with 544 recorded cases of intussusception found a nonsignificant decrease in intussusception (hazard ratio, 0.79 [95% confidence interval, 0.57–1.09]) in fully rotavirus-vaccinated children followed up to the age of 2 years.