Coronavirus Disease 2019: Associated Multiple Organ Damage. (21st June 2020)

• Record Type: Journal Article
• Authors: Collange, Olivier; Tacquard, Charles; Delabranche, Xavier; Leonard-Lorant, Ian; Ohana, Mickaël; Onea, Mihaela; Anheim, Mathieu; Solis, Morgane; Sauer, Arnaud; Baloglu, Seyyid; Pessaux, Patrick; Ohlmann, Patrick; Kaeuffer, Charlotte; Oulehri, Walid; Kremer, Stephane; Mertes, Paul Michel
• Is Part Of: Open forum infectious diseases. Volume 7:Number 7(2020)
• Publication Date: 2020-06-21
• Subjects: brain magnetic resonance imaging -- COVID-19 -- microthrombi -- SARS-CoV-2 -- severe acute respiratory syndrome; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa249
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: A 56-year-old man presented a particularly severe and multisystemic case of coronavirus disease 2019 (COVID-19). In addition to the common lung and quite common pulmonary embolism and kidney injuries, he presented ocular and intestinal injuries that, to our knowledge, have not been described in COVID-19 patients. Although it is difficult to make pathophysiological hypotheses about a single case, the multiplicity of injured organs argues for a systemic response to pulmonary infection. A better understanding of physiopathology should feed the discussion about therapeutic options in this type of multifocal damage related to severe acute respiratory syndrome coronavirus 2. Abstract : This patient with severe COVID-19 presented damage to five different organs: lungs, kidneys, brain, eyes and gut were injured. The multiplicity of injured organs argues for a systemic response to SARS-CoV-2 infection. "