0121 Effect of Total Sleep Deprivation on Word Recognition of Previously Studied Words with Different Emotional Valence. (27th May 2020)

• Record Type: Journal Article
• Authors: Hudson, A N; Whitney, P; Hinson, J M; Hansen, D A; Van Dongen, H; Honn, K A
• Is Part Of: Sleep. Volume 43(2020)Supplement 1
• Page Start: A48
• Page End: A48
• Publication Date: 2020-05-27
• Subjects: Sleep -- Physiological aspects -- Periodicals; Sleep disorders -- Periodicals; Sommeil -- Aspect physiologique -- Périodiques; Sommeil, Troubles du -- Périodiques; Sleep disorders; Sleep -- Physiological aspects; Sleep -- physiological aspects; Sleep Wake Disorders; Psychophysiology; Electronic journals; Periodicals; 616.8498
• DOI: 10.1093/sleep/zsaa056.119
• Languages: English
• ISSNs: 0161-8105

Abstract

Abstract: Introduction: Stimuli with an emotional valence tend to produce better recognition from memory than neutral stimuli. Sleep loss is believed to increase reactivity to negative stimuli, as compared to positive stimuli, which may comparatively enhance subsequent recognition from memory for negative stimuli. We investigated the impact of total sleep deprivation (TSD) on recognition accuracy for words with different emotional valence using the Affective Item Source Memory Task (AISM). Methods: N=14 adults (ages 21–39; 7 females) completed a 4-day in-laboratory study with 9h baseline sleep (22:00-07:00), 39h acute TSD, and 9h recovery sleep. The AISM was administered at 16:30 during baseline and after 34h TSD. During a 5min study phase, participants heard a list, twice, of 20 positive, 20 negative, and 20 neutral words spoken with a male or female voice. During an immediately subsequent 8min recognition phase, participants heard 120 words (50% new) and judged whether each word had been presented in the study list (item memory). For words judged to have been presented previously, participants indicated whether those were presented by a female or male speaker (source memory). Results: Mixed-effects ANOVA showed effects of session (p<0.001) and valence (p<0.001) on item memory. At baseline, accuracy was greatest for neutral and positive words compared to negative words. During TSD, accuracy declined for all three valences, and no interaction of session by valence was detected. No effects of TSD or valence on source memory were observed. Conclusion: Sleep deprivation reduced item memory for words of all valence types. However, there was no comparatively greater impact on item or source memory for negative words nor any differential effect of TSD for different valences. Whether our results would hold with longer time intervals between task phases or an intervening sleep period remains to be determined. Support: Jazz Pharmaceuticals