Relationship Between Olfactory Disturbance After Acute Ischemic Stroke and Latent Thalamic Hypoperfusion. (24th December 2019)

• Record Type: Journal Article
• Authors: Okamoto, Kazuhiro; Shiga, Hideaki; Nakamura, Hisako; Matsui, Makoto; Miwa, Takaki
• Is Part Of: Chemical senses. Volume 45:Number 2(2020)
• Page Start: 111
• Page End: 118
• Publication Date: 2019-12-24
• Subjects: brain injury -- cerebral perfusion -- human brain -- olfaction -- thalamus; Chemical senses -- Periodicals; 612.8
• DOI: 10.1093/chemse/bjz077
• Languages: English
• ISSNs: 0379-864X

Abstract

Abstract: Odor detection, recognition, and identification were assessed in 19 acute ischemic stroke patients who had no magnetic resonance imaging-detectable thalamic lesions but in whom technetium-99m ethyl cysteinate dimer single photon emission tomography revealed thalamic hypoperfusion. Although these patients were unaware of reduced olfactory function, they exhibited significantly lower scores in tests for odor identification and recognition threshold as compared with 9 ischemic stroke controls that had normal thalamic hypoperfusion. However, absolute odor detection thresholds were similar in the 2 groups. These results demonstrate the usefulness of cerebral perfusion scintigraphy in assessing sensory loss after ischemic stroke and provide further evidence for the role of the thalamus in olfaction.